Assessment of dyslipidemia among hypertensive pregnant women in Gaza Strip

Atef Masad
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Abstract

The aim of this study is to assess dyslipidemia status among hypertensive pregnant women and to correlate with preeclampsia in Gaza Strip. A cross sectional study was conducted on 85 pregnant women attending the Gynecology and Obstetrics Department of tertiary care in Gaza Strip (49-hypertension pregnant woman as patients and 36 normal pregnant women without hypertension as a control). Pregnancy induced hypertension (PIH) was found to be associated with fetus sex and it was higher with male fetus 28.6 % and twins 12.2% compared with control. The majority of the PIH patient were obese BMI (32.9 ±4.6) compared with control (25.7±3.5) (P < 0.001). Serum cholesterol, triglycerides, LDL-C, among PIH patients were high (175.3±56.6, 226.9±130.1, 67.4±51.4 mg/dl) respectively, compared with control (143.8±44.1, 186.3 ±101.3, 48.9±46.5 mg/dl) respectively. Abnormal lipid profile and low HDL-C levels may add to the promotion of vascular dysfunction during pregnancy and may induce hypertension and eventually pre-eclampsia and serious complications of fetus.
加沙地带高血压孕妇血脂异常的评估
本研究的目的是评估加沙地带高血压孕妇的血脂异常状况及其与先兆子痫的相关性。本研究对加沙地带三级医院妇产科的85名孕妇进行了横断面研究(49名高血压孕妇作为患者,36名无高血压的正常孕妇作为对照)。妊高征(PIH)与胎儿性别有关,与对照组相比,男胎高28.6%,双胞胎高12.2%。PIH患者BMI(32.9±4.6)高于对照组(25.7±3.5)(P < 0.001)。PIH患者血清胆固醇、甘油三酯、LDL-C分别为175.3±56.6、226.9±130.1、67.4±51.4 mg/dl,高于对照组(143.8±44.1、186.3±101.3、48.9±46.5 mg/dl)。血脂异常和低HDL-C水平可促进妊娠期血管功能障碍,并可诱发高血压,最终诱发子痫前期和严重的胎儿并发症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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