Haldi, Lemon and Methi

Journal of Chemistry: Education Research and Practice Pub Date : 2020-01-09 DOI:10.33140/jcerp.04.01.01

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Abstract

High plasma lipids interact with free radicals in human body leading to develop coronary artery disease. We in this study have compared hypolipidemic effects of Fenugreek, Curcuma longa, and Lemon. Study was conducted at Jinnah Hospital Lahore-Pakistan from January 2016 to May 2016. Ninety hyperlipidemic patients of age group 19 to 70 were included in the study. Exclusion criteria were diabetic, alcoholic additives, hypertensive patients and those whose kidney or liver functions were impaired. Consent was taken from all participants. Their base line lipid profile was taken in biochemistry laboratory of the hospital. They were divided in three groups i.e. 30 patients in each group. Group-I was advised to take 500 mg of Curcuma longa (haldi) mixed in fresh milk without cream, thrice daily for two months. Group-II patients were advised to take 100 grams of Fenugreek leaves mixed with salad in each meal (thrice daily) for the period of two months. Group-III patients were advised to take 40 ml of fresh lemon juice mixed with 40 ml mineral water thrice daily for two months. They all were advised not to take heavy meal rich with any type of fat like junk food etc. One hour daily brisk walk was advised to all participants. 15 days follow up visit was scheduled for them. After two months their lipid profile was re-determined. When results were compiled and statistically analyzed by applying paired ‘t’ test, it revealed that Curcuma longa decreased total cholesterol, TG, LDL cholesterol 16.10, 20.01, and 17.59 mg/dl respectively. Fenugreek decreased total cholesterol, TGs, and LDL cholesterol 14.70, 17.33, and 17.06 mg/dl respectively. Lemon in two months therapy decreased total cholesterol, TGs, and LDL cholesterol 15.45, 10.13, and 11.97 mg/dl respectively. None of the above mentioned herbs raised HDL cholesterol significantly. It was concluded from this research work that Curcuma longa, Fenugreek leaves and Lemon are mild to moderately effective hypolipidemic herbs to lower total plasma cholesterol, triglycerides, and LDL cholesterol but have no potential to raise HDL cholesterol when analyzed biostatistically

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高血脂与人体内自由基相互作用导致冠状动脉疾病的发生。我们在本研究中比较了葫芦巴、姜黄和柠檬的降血脂作用。研究于2016年1月至2016年5月在巴基斯坦拉合尔真纳医院进行。90例高脂血症患者，年龄19 ~ 70岁。排除标准为糖尿病、酒精添加剂、高血压患者和肾功能或肝功能受损的患者。获得了所有参与者的同意。基线脂质谱在医院生化实验室采集。他们被分为三组，每组30名患者。第一组建议服用姜黄500毫克，与鲜奶混合，不加奶油，每日三次，连续服用两个月。ii组患者建议每餐服用100克葫芦巴叶混合沙拉(每天三次)，为期两个月。iii组患者服用新鲜柠檬汁40 ml混合矿泉水40 ml，每日3次，连续2个月。他们都被建议不要吃油腻的食物，如垃圾食品等。建议所有参与者每天快走一小时。随访时间为15天。两个月后，重新测定他们的血脂。结果显示，姜黄可降低总胆固醇16.10 mg/dl、TG 20.01 mg/dl、低密度脂蛋白胆固醇17.59 mg/dl。葫芦巴分别降低总胆固醇、总总胆固醇和低密度脂蛋白胆固醇14.70、17.33和17.06 mg/dl。柠檬在两个月的治疗中降低了总胆固醇、总总胆固醇和低密度脂蛋白胆固醇，分别为15.45、10.13和11.97 mg/dl。以上提到的草药都不能显著提高高密度脂蛋白胆固醇。本研究结果表明，姜黄、胡芦巴叶和柠檬对降低血浆总胆固醇、甘油三酯和低密度脂蛋白胆固醇有轻度至中度的降血脂作用，但对提高高密度脂蛋白胆固醇没有作用

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Journal of Chemistry: Education Research and Practice

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