Acute ST-elevation myocardial infarction in a patient with polycystic kidney disease in Kano, Nigeria

Abstract

A 37-year-old male patient known to have polycystic kidney disease (PKD) for the past 5 years presented with a 2-day history of severe chest pain at rest that was confirmed as acute inferior myocardial infarction (MI). He was a known hypertensive for the past 5 years with a difficult-to-control blood pressure, but with preserved renal function. He had no family history of similar illness and has no personal history of diabetes mellitus, dyslipidemia, smoking, alcohol consumption, or recreational drugs use. Apart from elevated blood pressure of 150/100 mmHg, physical examination was unremarkable. He was found to have dyslipidemia with high-density lipoprotein cholesterol of 0.87 mmol/l and hypertriglyceridemia (2.7 mmol/l), but other serum lipid fractions and fasting plasma glucose were within normal limits. His echocardiogram showed normal sizes of all cardiac chambers with preserved left ventricular (LV) function, inferior wall hypokinesia, and Grade I LV diastolic dysfunction, and he had no aortic aneurysm. He was admitted for 5 days, treated conservatively, and discharged after resolution of symptoms, troponin, and raised ST segments. To the best of our knowledge, this is the first report from Nigeria illustrating the rare association between PKD and acute MI in the young.