Study of Demographic and Clinical Profile of Children with Indigenous Camphor Exposure Presenting at A Tertiary Care Centre

Bharathi Raja
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Abstract

Background: Small children have a tendency to put everything in the mouth; hence, poisoning due to accidental ingestion of commonly available household toxic substances is quite common in infants and small children. The aim of this retrospective study was to describe the demographic and clinical profile of children treated following exposure to camphor. Methods: A Retrospective descriptive study of children admitted with camphor poisoning from June 2018 to January 2020. The collected data were entered into a tabulated form, and descriptive statistical methods were used. Results: Of the 60 children studied, Male infants and toddlers were the most common victims of camphor induced illness. Oral route was the most common mode of exposure. The most common presenting symptom was symptomatic seizures of the generalised tonic clonic type (91.8%) followed by vomiting and fever. Most patients had seizure onset within 30 minutes of exposure that lasted for 5 to 10 minutes. 39% of those treated, required only a Benzodiazepines. Conclusion: Camphor causes neurological symptoms in young children and history of camphor exposure needs to be excluded in all cases of seizures. Ironically, most of them have not required long term AEDs on follow up. Neuroimaging done has no added benefit in prognosticating long term outcome in such children.
在三级保健中心出现的土著樟脑暴露儿童的人口统计学和临床概况研究
背景:小孩子有把任何东西都放进嘴里的倾向;因此,由于意外摄入常见的家用有毒物质而中毒在婴儿和儿童中很常见。这项回顾性研究的目的是描述暴露于樟脑后治疗的儿童的人口统计学和临床概况。方法:对2018年6月至2020年1月收治的樟脑中毒患儿进行回顾性描述性研究。收集到的数据以表格形式输入,并使用描述性统计方法。结果:在研究的60名儿童中,男性婴幼儿是樟脑诱发疾病的最常见受害者。口腔途径是最常见的暴露方式。最常见的症状是全身性强直性阵挛型的症状性发作(91.8%),其次是呕吐和发烧。大多数患者在接触后30分钟内癫痫发作,持续5至10分钟。39%的患者只需要服用苯二氮卓类药物。结论:樟脑可引起幼儿神经系统症状,所有癫痫病例均需排除樟脑接触史。具有讽刺意味的是,他们中的大多数人在随访时都不需要长期服用aed。神经影像学在预测此类儿童的长期预后方面没有额外的益处。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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