Coronarography in Patients with Factor XI deficiency: A Literature Review

Abstract

Hemophilia C or Factor XI deficiency is a hypocoagulable state leading to increased bleeding diathesis. Acute coronary syndrome can be manifested with chest pain and require a coronography to investigate the reason of the symptoms. This type of procedure requires the use of heparin and the possible need for oral antiplatelets especially if a stent was deployed. The use of anticoagulants or antiplatelets to prevent stent clotting becomes a challenge in patients with hypocoagulable state including patients with Hemophilia C. We will summarize in our review the approach taken in similar cases described in literature.