Global Analysis of Biomarker Responses in Aquatic Organisms Exposed to Contaminants

A. Bainy, M. R. Marques
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引用次数: 13

Abstract

Chemicals discharged into the environment may be taken up by aquatic organisms and elicit biological responses that can be used as biomarkers of exposure and/or effect. Depending on the site of action, they may be classified as neurotoxic, hepatotoxic, genotoxic, or hemato-immunotoxic biomarkers. Multiple molecular biomarker analysis can furnish a more precise diagnostic of effects induced by different classes of chemicals and provide a sensitive, physiologically based method of determining the presence of a contaminant and its bioavailability to aquatic organisms. This article addresses toxicity, mechanism of adaptation, as well as toxic damage induced by chemical exposure.
暴露于污染物的水生生物生物标志物反应的全球分析
排放到环境中的化学品可能被水生生物吸收并引起生物反应,可作为暴露和/或影响的生物标志物。根据作用部位的不同,它们可被分类为神经毒性、肝毒性、基因毒性或血液免疫毒性生物标志物。多分子生物标志物分析可以更精确地诊断由不同类别的化学物质引起的影响,并提供一种敏感的、基于生理学的方法来确定污染物的存在及其对水生生物的生物利用度。本文论述了化学物质的毒性、适应机制以及化学物质暴露引起的毒性损害。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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