Risk Profiling of Exposures to Potentially Toxic Metals PTM(S) Through Noodles Consumption. A Case Study of Human Health Risk Assessment

D. Jakkielska, Marcin Frankowski, I. Kurzyca, Anetta Ziołafrankowska
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Abstract

Abstract This study aimed to quantify levels of the toxic heavy metals metalloid arsenic (As), cadmium (Cd), lead (Pb) and mercury (Hg) in commercially available noodles. Analysis was performed via the acid microwave digestion method followed by inductively coupled plasma mass spectrometry (ICP-MS). Furthermore, the potential health risks resulting from the consumption of noodles by polish consumers were evaluated using the estimated average daily intake of heavy metals (ADIHMs; µg·kg−1 bw·day−1). Additionally, to assess the potential health consequences due to noodle consumption, the total hazard quotient (THQ) and cancer risk (CR) were calculated. The average contents of Pb, As, Cd, and Hg in instant noodle samples were determined as 9.241, 8.483, 29.39, and 1.661 µg·kg−1, respectively. THQ values for heavy metal toxicity were found to be below 1, indicating that the consumer is not exposed to carcinogenic health risks associated with the analyzed metals. Additionally, the rank order of max THQ was Pb < Cd < As < Hg, and the mean THQ was Pb < Hg < As < Cd, while both the max and mean CR rank orders were Pb < Cd < As.
食用面条接触潜在有毒金属PTM(S)的风险分析。人类健康风险评估个案研究
摘要本研究旨在量化市售面条中有毒重金属砷(As)、镉(Cd)、铅(Pb)和汞(Hg)的含量。采用酸微波消解法和电感耦合等离子体质谱法(ICP-MS)进行分析。此外,对波兰消费者食用面条造成的潜在健康风险进行了评估,使用估计的平均每日重金属摄入量(ADIHMs;µg·公斤−1 bw·天−1)。此外,为了评估由于面条消费的潜在健康后果,计算了总危害商(THQ)和癌症风险(CR)。方便面样品中Pb、As、Cd和Hg的平均含量分别为9.241、8.483、29.39和1.661µg·kg−1。重金属毒性的THQ值低于1,表明消费者没有接触到与所分析金属相关的致癌健康风险。最大THQ排序顺序为Pb < Cd < As < Hg,平均THQ排序顺序为Pb < Hg < As < Cd,最大和平均CR排序顺序为Pb < Cd < As。
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