Importance of atherothrombosis or thrombophilia in acute retinal vein occlusion

Y. Boduroğlu, N. Son
{"title":"Importance of atherothrombosis or thrombophilia in acute retinal vein occlusion","authors":"Y. Boduroğlu, N. Son","doi":"10.4103/njc.njc_22_18","DOIUrl":null,"url":null,"abstract":"Retinal vein occlussion (RVO) is one of the retinal vascular disease which may occur due to atherosclerosis in elderly, but young patients may have connective tissue diseases (such as systemic lupus erythematosus [SLE]) or thrombophilia. Antiphospholipid antibodies (lupus anticoagulant [LA], anticardiolipin [anti-CL]) are well-known risk factors for thrombotic complications in SLE. We present a case of SLE with RVO. A 57-year-old woman was admitted with decreasing of visual acuity (VA) in the right eye. She did not have diabetes mellitus or hypertension. Malar rash was found in the face. The ophthalmoscopy and fluorescein angiography showed retinal hemorrhages. LA antibody and antinuclear antibodies were positive, and level of anti-CL was normal with high level of homocysteine. Because of detecting widespread capillary nonperfusion in her retina, VA did not change during follow-up after treatment. RVO in SLE patients has been described to be caused by thrombophilic conditions.","PeriodicalId":228906,"journal":{"name":"Nigerian Journal of Cardiology","volume":"46 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nigerian Journal of Cardiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/njc.njc_22_18","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Retinal vein occlussion (RVO) is one of the retinal vascular disease which may occur due to atherosclerosis in elderly, but young patients may have connective tissue diseases (such as systemic lupus erythematosus [SLE]) or thrombophilia. Antiphospholipid antibodies (lupus anticoagulant [LA], anticardiolipin [anti-CL]) are well-known risk factors for thrombotic complications in SLE. We present a case of SLE with RVO. A 57-year-old woman was admitted with decreasing of visual acuity (VA) in the right eye. She did not have diabetes mellitus or hypertension. Malar rash was found in the face. The ophthalmoscopy and fluorescein angiography showed retinal hemorrhages. LA antibody and antinuclear antibodies were positive, and level of anti-CL was normal with high level of homocysteine. Because of detecting widespread capillary nonperfusion in her retina, VA did not change during follow-up after treatment. RVO in SLE patients has been described to be caused by thrombophilic conditions.
动脉粥样硬化血栓形成或血栓形成在急性视网膜静脉阻塞中的重要性
视网膜静脉闭塞(Retinal vein occlusion, RVO)是老年人因动脉粥样硬化而可能发生的视网膜血管疾病之一,但年轻患者可能存在结缔组织疾病(如系统性红斑狼疮[SLE])或血栓性疾病。抗磷脂抗体(狼疮抗凝剂[LA],抗心磷脂[anti-CL])是众所周知的SLE血栓性并发症的危险因素。我们报告一例SLE伴RVO。一位57岁的女性因右眼视力下降而入院。她没有糖尿病或高血压。脸上发现马拉疹。眼底镜及荧光素血管造影显示视网膜出血。LA抗体和抗核抗体阳性,抗cl水平正常,同型半胱氨酸水平高。由于在她的视网膜中发现了广泛的毛细血管非灌注,在治疗后的随访中VA没有改变。SLE患者的RVO被认为是由血栓性疾病引起的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信