Dynamics of Covid-19 Delta Variant in the UK: the estimate of Reproduction Number

Yujie Ni
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Abstract

Delta variant is considered as Variant of Concern (VOC) due to its high transmissibility compared to the original strain and other variants. This paper assessed the transmissibility of the delta variant in the UK from March to July by estimating effective reproduction numbers. First, effective reproduction number R at initial exponential phase of outbreak was calculated by using exponential growth method, then real time reproduction number Rt was estimated by using the time-dependent method. Depending on the observed generation interval distribution, R is 1.39 and Rt is merging to 1 along the time. The result is significantly lower than the basic reproduction number R0 reported by several institutions. From the first emergence of delta variant in UK to July, even though the daily infection cases were increasing due to step-by-step lockdown relaxation, the transmissibility of delta is slightly diminishing. Control measures especially the vaccination program are considered effective from this perspective. The analysis was performed based on daily cumulative delta infection number from March to July provided by Public Health England (PHE). R studio and Microsoft Excel were used in data processing and visualization.
英国新冠病毒δ型变异动态:繁殖数估计
由于与原始菌株和其他变体相比,Delta变体具有较高的传播率,因此被认为是关注变体(VOC)。本文通过估计有效繁殖数,评估了3月至7月英国delta变异的传播率。首先采用指数增长法计算爆发初始指数期的有效繁殖数R,然后采用时间依赖法估计实时繁殖数Rt。根据观测到的代间隔分布,R为1.39,Rt随时间趋近于1。该结果明显低于多家机构报道的基本繁殖数R0。从英国首次出现delta变体到7月,尽管由于逐步放松封锁,每天的感染病例有所增加,但delta的传播力略有下降。从这个角度来看,控制措施特别是疫苗接种计划被认为是有效的。分析是根据英国公共卫生部(PHE)提供的3月至7月每日累积德尔塔感染数进行的。使用R studio和Microsoft Excel进行数据处理和可视化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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