[Research on myasthenia gravis in children with HLA supratype].

Abstract

38 cases of MG Children's patients were typed for HLA-I, II and III antigens. It shows that MG significantly associated with HLA-A2, Bw46 and DRw9. Their relative risk were 3.60, 8.18. 4.60, Pc < 0.05 or 0.001 respectively. The association with C4 and Bf were not found. Aw19 is seemed as a protection factor of this disease. These results are similar with the research on Chinese MG patients in Hong Kong but are quite different with those of caucasian data.