[The intracellular pH of the peripheral blood lymphocytes in cattle during the development of leukemia].

Abstract

The intracellular pH distribution of peripheral cattle lymphocytes has been studied in normal state and at six stages of the development of bovine leukosis by the dye microfluorimetry of single cells. It has been shown that the increase of mean intracellular pH value occurs as well some distribution parameters, such as pH range and asymmetry change during the disease process. Probable reasons responsible for the observed modification of the distribution pattern are discussed.