Do Center Proteins in Vitamin-Related Network Tend to Be Vitamin D-Related?

Abstract

Biological networks have been widely interest as an emergent research field over the past decade. Considering of the structure of a network would helpful for understanding its function, determining the pivotal composition in the biological networks is an important step toward understanding them, and the key insights have been provided with centrality analysis in recent years. In the present paper, using 10 centrality approaches, we study the structure of a vitamin-related protein-protein interaction network. The results reaffirm Nguyen et al. 's find from 2 points, and suggest that center proteins in vitamin-related network tend to be vitamin D-related.