Ca Cervix with Bilateral Ovarian Metastasis: An Interesting Case Report with Review of Literature

Manas Dubey, V. Trivedi, R. Chauhan, R. Rani, U. Singh, R. Anirudha, Podder, A. Hussain
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Abstract

Globally the estimated age-standardised incidence of cervical cancer was 13·1 per 100, 000 women and with varied rates ranging from 2 to 75 per 100,000 women in different countries [1]. In India overall cervical cancer incidence is 8.4% [2]. For patients with early stage cervical cancer Ib1, Ib2 and IIa1, Radical hysterectomy with pelvic lymphadenectomy with Bilateral Salpingo opherectomy is a reasonable therapeutic option [3]. For locally advanced stage Concurrent–Chemoradiation is the primary Radical treatment modality [4]. Ovarian Metastases from squamous cell carcinoma (SCC) of the cervix are rare and reported in less than 1% of early stage cervical SCC [5]. Studies reported that greater than 1.3% of cell carcinomas of cervix present with ovarian metastases [5–7]. Ovarian function preservation is critical for quality of life, especially for young patients (<45 years old). Preservation can be performed directly in situ or by ovarian transposition during surgery. Here, we are presenting a very unusual rare case of Ca Cervix with Bilateral Ovarian metastasis along with literature review. 2. CASE PRESENTATION
宫颈癌伴双侧卵巢转移:一例有趣的病例报告并文献复习
在全球范围内,宫颈癌的年龄标准化发病率估计为每10万名妇女13.1例,不同国家的发病率从每10万名妇女2例到75例不等[1]。在印度,宫颈癌的总发病率为8.4%[2]。对于早期宫颈癌Ib1、Ib2、IIa1患者,根治性子宫切除术+盆腔淋巴结切除术+双侧输卵管切除术是一种合理的治疗选择[3]。对于局部晚期,同步放化疗是主要的根治性治疗方式[4]。宫颈鳞状细胞癌(SCC)的卵巢转移是罕见的,据报道不到1%的早期宫颈鳞状细胞癌[5]。有研究报道,超过1.3%的宫颈细胞癌存在卵巢转移[5-7]。卵巢功能的保存对生活质量至关重要,特别是对年轻患者(<45岁)。保存可以直接在原位进行,也可以在手术中通过卵巢移位进行。在此,我们报告一例罕见的宫颈癌合并双侧卵巢转移病例,并结合文献复习。2. 案例展示
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