Cross-Sectional Study Design and Data Analysis of the Effect of Chitin NanofibrilsLignin Micro/Nano Particles on Malaysia’s Subjects with Skin Disorders

Jui Yy, Ching Tl, Ing Ts, Cardillo M, Gagliardini A, M. P
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引用次数: 1

Abstract

Objective: The Objective of the paper is to control the activity of innovative Cosmetic products, classified as Cosmeceuticals because of their particular effectiveness and used alone without consume of drugs, to verify their efficacy on subjects affected by acne, contact dermatitis, and photoaging. After an introduction reporting some data on the cosmetic market in Malaysia and their habit of mind to attend the Beauty Centers before going to dermatologist, we report the method of treatment by cosmetic products organized by 90 voluntary subjects, divided in three groups of 30 subjects, affected by photo-aging, acne and contact dermatitis respectively. They were treated for 90 days and two times a week into a Malaysian Beauty center by different Cosmetic emulsions based on the use of chitin nanofibrils-lignin micro/nanoparticles bound to different selected active ingredients, such as nicotinamide, antioxidants and glycolic acid. The same products were used at home in the morning and evening for all the in study period. Treatments into the Beauty Center and at home were under the control of a Dermatologist and expert beauticians for all the period of experimentation and the control was verified by the score method and photosat the starting day and after 30, 60, 90 days of treatment and 120 days (follow up visit). The obtained results, controlled by a dermatologist by score methods and photos, have shown the possibility to use well formulated cosmetics to try to ameliorate the reported diseases, without the use of topical and/or systemic drugs. In conclusion, these innovative cosmeceutical, used by the help of expert beauticians, may be of great help to Dermatologists and Plastic surgeons to solve some skin problems, avoiding the use of drugs, or limiting their doses to lessen the risk of harmful side effects.
几丁质纳米原纤维和木质素微/纳米颗粒对马来西亚皮肤疾病患者影响的横断面研究设计和数据分析
目的:本文的目的是控制创新化妆品的活性,这些化妆品因其特殊的有效性而被归类为药妆品,并且在不消耗药物的情况下单独使用,以验证其对痤疮,接触性皮炎和光老化受影响的受试者的功效。在介绍了马来西亚化妆品市场的一些数据和他们在去皮肤科医生之前去美容中心的习惯之后,我们报告了90名志愿者组织的化妆品治疗方法,他们被分为三组,每组30人,分别受到光老化,痤疮和接触性皮炎的影响。他们在马来西亚美容中心接受了90天的治疗,每周两次,使用不同的化妆品乳液,这些乳液是基于几丁质纳米原纤维的使用,木质素微/纳米颗粒与不同的选定活性成分结合,如烟酰胺、抗氧化剂和乙醇酸。在整个研究期间,每天早晚在家中使用相同的产品。在整个实验期间,进入美容中心和在家治疗的患者均由皮肤科医生和专业美容师进行控制,并在开始当天、治疗30天、60天、90天和120天(随访)后用记分法进行验证和拍照。由皮肤科医生通过评分方法和照片控制的所得结果表明,可以使用配方良好的化妆品来尝试改善所报告的疾病,而无需使用局部和/或全身药物。总之,这些创新的药妆,在专业美容师的帮助下使用,可能会对皮肤科医生和整形外科医生有很大的帮助,以解决一些皮肤问题,避免使用药物,或限制其剂量,以减少有害副作用的风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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