Role of Polyphenols in Preventing Prostate Cancer Cell Growth through Calcium Channel Blockers: An Overview

Abstract

Prostate cancer (PCa) is the second most widely diagnosed cancer in men and the sixth leading cause of death among them due to cancer. Phytochemicals play a significant role in chemo preventions. Recently, an increasing number of studies have looked into the role of polyphenols with regard to prostate cancer cell growth, highlighting their ability to target various cellular mechanisms. For this reason, we specifically focused on the studies published in the last twenty years by using different search engines including Google Scholar, PubMed, Web of Sciences, and Scopus in order to select and identify the potential role of polyphenols in targeting prostate cancer through calcium channel blockers. We concluded that polyphenols are the primary chemopreventive agents for prostate cancer. Keywords: calcium channel blocker, cancer, chemopreventive, polyphenols, prostate cancer Copyright(c) The Author