Assessment of Treatment Outcomes of Tuberculosis patients in a Rural Comprehensive Health Care Centre, Benue State, North Central Nigeria

O. Ogbeyi, L. Luret, S. Ogiri, T. Aforlaranrami, SA Igbabul
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Abstract

Despite the availability of effective intervention programs over the years, tuberculosis remains a major global health problem. It causes ill-health among millions of people each year and ranks alongside the Human immunodeficiency virus (HIV) as a leading cause of death worldwide. The aim of this study is to assess the outcome of tuberculosis treatment in a Rural Primary Health Care Centre, Benue State, North Central Nigeria. A three-year retrospective study was employed to review 150 tuberculosis cases treated from January 2014 - December 2016. Data were analysed using Statistical Package for Social Sciences (SPSS) version 20 and presented as tables and charts. The relationship between independent and outcome variables were tested with Chi-square test and P-value was set at 0.05. Of the 150 Tuberculosis patients treated, 84(56.0%) were males while 66(44.0%) were females. More than two-thirds (77.3%) of the patients had pulmonary tuberculosis. The successful treatment rate was 60.0% (32.7% treatment completed and 27.3% cured). Over twelve percent defaulted, 10.7% were lost to follow up, 6.7% were transferred out and 0.7% died. In this study, the successful treatment outcome was lower than the National target .The relationship between the disease sites; HIV status, Cotrimoxazole prophylaxis and the treatment outcome were statistically significant. Directly Observed Treatment Short Course (DOTS) providers should address issue of hindrances to adherence to treatment in order to improve the treatment success rate.
尼日利亚中北部贝努埃州农村综合保健中心结核病患者治疗结果评估
尽管多年来已有有效的干预方案,但结核病仍然是一个主要的全球健康问题。它每年导致数百万人的健康状况不佳,与人类免疫缺陷病毒(HIV)并列,是世界范围内导致死亡的主要原因。本研究的目的是评估尼日利亚中北部贝努埃州农村初级卫生保健中心结核病治疗的结果。一项为期三年的回顾性研究对2014年1月至2016年12月接受治疗的150例结核病病例进行了回顾。使用社会科学统计软件包(SPSS)第20版对数据进行分析,并以表格和图表的形式呈现。自变量与结局变量之间的关系采用卡方检验,p值为0.05。150例肺结核患者中,男性84例(56.0%),女性66例(44.0%)。超过三分之二(77.3%)的患者患有肺结核。治疗成功率为60.0%(治疗完成率32.7%,治愈率27.3%)。超过12%的人违约,10.7%的人失去了跟踪,6.7%的人被转移出去,0.7%的人死亡。在本研究中,成功的治疗结果低于国家目标。HIV状态、复方新诺明预防和治疗结果均有统计学意义。直接观察短程治疗(DOTS)提供者应解决阻碍坚持治疗的问题,以提高治疗成功率。
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