Optimization of gold thin films thicknesses in enhancing SPR response

N. F. Murat, W. M. Mukhtar, A. Rashid, K. A. Dasuki, A. A. R. A. Yussuf
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引用次数: 18

Abstract

Nowadays, surface plasmon resonance (SPR) sensor has been widely used in biosensing applications to detect the wide diversity of biomolecular interactions. There are few parameters need to be concerned in order to optimize the performance of SPR sensors such as film thicknesses, type of thin films and their configurations. In this study, we seek to determine the optimum thicknesses of hybrid thin films which consist of gold-graphene oxide layers for the enhancement of SPR sensor sensitivity. By using a theoretical approach, a WINSPALL 3.02 simulator had been used to investigate the effects of various thicknesses of hybrid configuration's thin films towards the excitation of surface plasmon polaritons (SPP). A layer of 3 nm protein was added to compare the maximum adsorption of the SPR sensor based on their configuration. It was found that the optimum thicknesses of gold and graphene oxide are 50 nm and 0.68 nm respectively for achieving best sensitivity. Thus, the sensitivity value for gold-GO thin films is higher than silver-GO which are 19.42 °/RIU and 5.45 °/RIU with FWHM = 2.28° and 0.64° respectively.
优化金薄膜厚度提高SPR响应
目前,表面等离子体共振(SPR)传感器已广泛应用于生物传感领域,用于检测生物分子相互作用的多样性。为了优化SPR传感器的性能,需要考虑的参数很少,如薄膜厚度、薄膜类型和它们的结构。在本研究中,我们试图确定由金-氧化石墨烯层组成的杂化薄膜的最佳厚度,以增强SPR传感器的灵敏度。采用理论方法,利用WINSPALL 3.02仿真器研究了不同厚度杂化结构薄膜对表面等离子激元(SPP)激发的影响。加入一层3nm的蛋白,比较两种结构对SPR传感器的最大吸附效果。研究发现,金和氧化石墨烯的最佳厚度分别为50 nm和0.68 nm,可获得最佳灵敏度。因此,金氧化石墨烯薄膜的灵敏度值高于银氧化石墨烯薄膜,分别为19.42°/RIU和5.45°/RIU, FWHM分别为2.28°和0.64°。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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