Is it really Necessary to Eradicate Helicobacter pylori?

Abstract

Helicobacter pylori is a Gram-negative bacterium that colonizes around 50% of world population. It is frequently associated with gastrointestinal diseases such as gastritis, peptic ulcer, and in some cases, can favour the development of gastric cancer. After the host colonization, H. pylori can cause chronic infection and disease in less than 10% of symptomatic individuals after several years. Thus, the apparent colonization of H. pylori requires a long time of establishment and the continuous stimulation of the inflammatory response to produce enough histological deterioration for disease expression [1].