C. T. White, Raj K. Singh, Peter B. Reintjes, J. Lampe, B. W. Erickson, W. Dettloff, V. Chi, S. Altschul
{"title":"BioSCAN: a VLSI-based system for biosequence analysis","authors":"C. T. White, Raj K. Singh, Peter B. Reintjes, J. Lampe, B. W. Erickson, W. Dettloff, V. Chi, S. Altschul","doi":"10.1109/ICCD.1991.139959","DOIUrl":null,"url":null,"abstract":"A special-purpose computer system has been designed to accelerate scanning large databases of DNA and protein sequences (biosequences) for patterns of interest. The system consists of a custom-designed circuit board installed in a host workstation and associated software. The board features a variable number of identical full-custom ASICs. Each biological sequence comparative analysis node. (BioSCAN) ASIC, in turn, features a large one-dimensional systolic array of identical processing elements (PEs). The BioSCAN system scans approximately two million database elements per second. For typical problems this results in a 1000-fold speedup over current workstations.<<ETX>>","PeriodicalId":239827,"journal":{"name":"[1991 Proceedings] IEEE International Conference on Computer Design: VLSI in Computers and Processors","volume":"21 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1991-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"41","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"[1991 Proceedings] IEEE International Conference on Computer Design: VLSI in Computers and Processors","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/ICCD.1991.139959","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 41
Abstract
A special-purpose computer system has been designed to accelerate scanning large databases of DNA and protein sequences (biosequences) for patterns of interest. The system consists of a custom-designed circuit board installed in a host workstation and associated software. The board features a variable number of identical full-custom ASICs. Each biological sequence comparative analysis node. (BioSCAN) ASIC, in turn, features a large one-dimensional systolic array of identical processing elements (PEs). The BioSCAN system scans approximately two million database elements per second. For typical problems this results in a 1000-fold speedup over current workstations.<>