Diagnostic Challenge: Occupational Rhinitis

O. Sílvia, R. João, J. Maria, L. Noémia, Matos Sara, L. Nuno
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Abstract

Occupational rhinitis is a work-related disease that results from nasal exposure to toxic and harmful substances in the workplace. Both allergic and nonallergic mechanisms may be involved. It has a very typical presentation and worsens with continued exposure. There is a very wide list of substances that cause this disease, mainly products associated with ammonia. The diagnosis is made based on the clinical manifestations and the first line treatment is the cessation of exposure. The authors present a case report of a 52-year-old woman, who worked as laboratory assistant in techniques of biology, physics and chemistry, in a secondary school, for 20 years. Preparation of ammoniacal solutions and solutes in association with the manipulation of the products without personal protective equipment, led to the development of a clinical picture compatible with the diagnosis of occupational rhinitis. In the clinical history, the symptomatology described by the patient worsened in periods of labor exposure and was absent in vacation periods, which is typical of occupational pathology. Several treatments were attempted, medical and surgical, before occupational rhinitis was suspected. However, improvement of the clinical picture with work reallocation, led to the assumption that occupational rhinitis was the most likely diagnosis. This case demonstrates that the diagnosis of occupational rhinitis can be easily missed, if we ignore the occupational exposure of patients, which can lead to unnecessary and costly medical interventions, since the only effective treatment is the cessation of exposure to the causal agent.
诊断挑战:职业性鼻炎
职业性鼻炎是一种与工作有关的疾病,由鼻腔接触工作场所的有毒有害物质引起。可能涉及过敏和非过敏机制。它有一个非常典型的表现,并随着持续接触而恶化。导致这种疾病的物质有很多,主要是与氨有关的产物。诊断是根据临床表现作出的,第一线治疗是停止接触。作者报告了一名52岁妇女的病例报告,她在一所中学担任生物、物理和化学技术实验室助理20年。氨溶液和溶质的制备与没有个人防护设备的产品操作相关,导致了与职业性鼻炎诊断相容的临床图像的发展。在临床病史中,患者所描述的症状在劳动暴露期间加重,在休假期间无症状,这是典型的职业病理。在怀疑是职业性鼻炎之前,尝试了几种药物和手术治疗。然而,临床图像的改善与工作的重新分配,导致假设职业性鼻炎是最有可能的诊断。这个病例表明,职业性鼻炎的诊断很容易被遗漏,如果我们忽视患者的职业暴露,这可能导致不必要和昂贵的医疗干预,因为唯一有效的治疗方法是停止接触致病因子。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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