When Should the Sternum Be Closed After Aortic Surgery?

Veysel Başar, F. Yiğit, Fariz Jafarov, H. Sunar
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Abstract

Introduction: There are many factors affecting postoperative morbidity and mortality in patients managed with delayed sternal closure (DSC) after aortic surgery. This study aimed to examine the postoperative management of patients after DSC and the factors affecting morbidity and mortality. Patients and Methods: Among 2151 patients who underwent ascending aorta and/or aortic valve surgery between January 2012 and December 2020, 64 patients managed with DSC were included in the study. The records of the patients were obtained from the hospital archive/hospital electronic database. Postoperative day 30 was determined as early mortality. Results: Uncontrollable bleeding 34.4% (n= 22), LCOS (Low Cardiac Output Syndrome) 31.4% (n= 20) and mediastinal edema 28.1% (n= 18)were the main causes for DSC. In the remaining patients (6.3%, n= 4), DSC was preferred for other non-specific reasons such as uncontrollable arrhythmia. Forty-five patients’ chests (70.3%) were closed in the postoperative period, and 19 patients (29.7%) could not be closed due to death (p< 0.001). Early mortality was observed in 27 patients (42.2%), and sepsis was observed in 10 patients (15.6%). Deep sternal wound infection (DSWI) was present in 4.7% of the patients and the rate of sepsis was higher in this patient group (66.7%-13.1%, p< 0.05). There was no statistically significant difference in the probability of sepsis in the culture-positive patient group (p> 0.05). However, the closure time was longer in patients with a previous operation history, postoperative acute renal failure, surgical site infection, and postoperative bleeding revision/surgical revision (p< 0.05). Conclusion: DSC can be preferred as a life-saving method for various reasons such as bleeding diathesis, mediastinal edema, and malignant arrhythmia after open-heart surgery. Accurate timing and close follow-up are important for sternal closure. In these patients, a multidisciplinary approach is required in the postoperative period.
主动脉手术后胸骨何时关闭?
影响主动脉术后延迟胸骨关闭(DSC)患者术后发病率和死亡率的因素有很多。本研究旨在探讨DSC患者的术后处理及影响发病率和死亡率的因素。患者和方法:在2012年1月至2020年12月期间接受升主动脉和/或主动脉瓣手术的2151例患者中,64例接受DSC治疗的患者被纳入研究。患者的记录来自医院档案/医院电子数据库。术后第30天确定为早期死亡。结果:无法控制的出血34.4% (n= 22),低心输出量综合征(LCOS) 31.4% (n= 20),纵隔水肿28.1% (n= 18)是DSC的主要原因。其余患者(6.3%,n= 4),由于其他非特异性原因,如不可控心律失常,首选DSC。术后闭合45例(70.3%),死亡不能闭合19例(29.7%)(p< 0.001)。早期死亡27例(42.2%),败血症10例(15.6%)。胸骨深创面感染(DSWI)发生率为4.7%,脓毒症发生率高于对照组(66.7% ~ 13.1%,p< 0.05)。培养阳性患者组脓毒症发生概率比较,差异无统计学意义(p> 0.05)。有手术史、术后急性肾功能衰竭、手术部位感染、术后出血翻修/手术翻修的患者闭合时间较长(p< 0.05)。结论:对于心内直视术后出血、纵隔水肿、恶性心律失常等多种原因,DSC均可作为首选的抢救方法。准确的时机和密切的随访对胸骨闭合至关重要。对于这些患者,术后需要多学科联合治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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