Adult T Cell Lymphoma/Leukaemia with Renal Infiltration: A Case Report from Sri Lanka

Abstract

Adult T Cell Leukaemia/Lymphoma (ATLL) is a rare T cell lymphoproliferative disease associated with Human T Cell Lym-photropic Virus-1 (HTLV1) endemic in some parts of the world and therefore has a distinct demographic distribution. There are no cases of ATLL reported in Sri Lanka thus far hence this is the first reported case. Renal parenchymal infiltration in ATLL is ex - tremely rare. Due to the rarity of the disease, evidence-based standard therapeutic options are lacking. The outcome of patients with ATLL is poor, particularly in the relapsed and refractory settings. Here we report a case of ATLL with renal involvement that initially responded to combined chemotherapy but later regressed to refractory disease with poor response to combined immunotherapy and antiviral therapy.