Exploring hormone communication and perception of emotion

Jeffrey Jenkins, Lin- Ching Chang, Binh Q. Tran, H. Szu
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Abstract

Are the biological mechanisms that facilitate perception of external photon stimuli using the sense of sight also responsible for the perception of internal hormone stimuli using the instinctive sense of emotion? Different regions of the body influence one another by communicating on the molecular scale with small electrical ions as well as larger chemical macromolecules such as hormones. For example, the detection of a predator causes hormones to be produced throughout the body, leading to a rapid physical response. To model such a system, we divide biological phenomena into two stages: sensing and communication, where each stage uses electrical ions and various molecules as signals. Designing a biomimetic computer system that can perform such a task is currently a challenge due to the large size of biological macromolecules and the small size of digital electronic components that are suited for electrons. We derive a general molecular communication theory to describe the interaction of molecules on different time and space scales with a thermodynamic model of hormone equilibration based on the Minimization of Helmholtz Free Energy (MFE). Our work paves the way for future cutting-edge AI systems to utilize heterogenous units of information and as a result, more accurately resembles the style of computation performed by biological systems.
探索荷尔蒙交流和情感感知
促进使用视觉感知外部光子刺激的生物机制是否也负责使用本能的情感感知内部激素刺激?身体的不同区域通过在分子尺度上与小的电离子以及较大的化学大分子(如激素)进行交流来相互影响。例如,发现捕食者会导致全身产生激素,导致快速的身体反应。为了模拟这样一个系统,我们将生物现象分为两个阶段:传感和通信,其中每个阶段都使用电子离子和各种分子作为信号。由于生物大分子的大尺寸和适合电子的数字电子元件的小尺寸,设计一个能够执行这样一项任务的仿生计算机系统目前是一个挑战。利用基于亥姆霍兹自由能最小化(MFE)的激素平衡热力学模型,导出了描述分子在不同时间和空间尺度上相互作用的一般分子通信理论。我们的工作为未来尖端的人工智能系统利用异构信息单元铺平了道路,因此,更准确地类似于生物系统执行的计算风格。
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