Visualization of Simulated Arrhythmias due to Gap Junctions

A. Ienna, M. Migliore, Cesare Valenti
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Abstract

New computational models are able to simulate details of cardiac cell networks. Their results allow a better understanding of the functionality of the heart and suggest possible actions to reduce non-fatal premature beats that can give rise to serious diseases. We developed a user-friendly interface to organize Neuron simulations and to present in real-time a three-dimensional representation of the electrical activity due to the gap junctions which interconnect the cells inside cardiac tissues. All physiological parameters were set according to real experimental observations and compared against different types of arrhythmias, retrieved from the Physionet Data Base.
由间隙连接引起的模拟心律失常的可视化
新的计算模型能够模拟心脏细胞网络的细节。他们的研究结果有助于更好地了解心脏的功能,并提出可能采取的措施,以减少可能导致严重疾病的非致命性早搏。我们开发了一个用户友好的界面来组织神经元模拟,并实时呈现由心脏组织内细胞相互连接的间隙连接引起的电活动的三维表示。所有生理参数均根据实际实验观察设置,并与从Physionet数据库检索的不同类型的心律失常进行比较。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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