Prevalence of carbapenemase producing gram negative bacteria in renal failure urinary tract infection patients in Tikrit City, Iraq

Abstract

The kidneys’ ability to operate declines slowly and creatively as a result of chronic renal disease. It frequently results from issues with other serious medical disorders (such as spinal cord defects, hypertension, and diabetes). Due to the increased chances of acquiring end-stage renal disease (ESRD) patients, there is a higher incidence of multidrug-resistant organisms in the community, primarily methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE). It is also poorly understood how gram-negative bacteria that produce carbapenemase affect ESRD patients on RRT (replacement renal treatment). 39 patients with urinary tract infections and renal failure participated in this study to determine the prevalence of gram-negative bacteria and Enterobacteriaceae that produce carbapenemase in Tiktit city. Disc diffusion method was used to determine whether the isolated and cultured bacteria were carbaqpenemase producing. According to the present study prevalence of carbapenemase producing group among renal failure patient with UTI was (78%), and not carbapenemase group was 22%. The females percentage was 40.6 % and male’s percentage was 37.5%, recurrent UTI infections history for; renal failure patients was very high 73% and in males 40% more than females 34%.