Sublingual immunotherapy (SLIT) in a standard American allergy practice

R. Garcia-Ibanez, D. Pollina
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Abstract

Subcutaneous Immunotherapy (SCIT) has been used in the United States with little modification for almost 100 years. It has been proven effective in the treatment of allergic disease not responsive to pharmacotherapy and appears to prevent the emergence of asthma in the pediatric population affected with allergic rhinitis. It is also effective in the treatment of Hymenoptera venom allergy, and drug allergy. The standard protocol for the treatment of all allergic disease requires injections twice a week for up to 6 months with maintenance biweekly or monthly shots lasting 3 to 5 years. Rush schedules are also possible though they appear to carry higher risks to patients.
舌下免疫治疗(SLIT)在标准的美国过敏实践
皮下免疫疗法(SCIT)在美国已经使用了近100年,几乎没有修改。它已被证明在治疗对药物治疗无反应的过敏性疾病方面是有效的,并且似乎可以预防过敏性鼻炎患儿哮喘的出现。对膜翅目毒液过敏、药物过敏也有较好的治疗效果。治疗所有过敏性疾病的标准方案要求每周注射两次,持续6个月,维持每两周或每月注射一次,持续3至5年。匆忙的时间表也是可行的,尽管它们似乎对患者有更高的风险。
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