Cheng-Hsiang Cheng, Ping-Yuan Tsai, Tzu-Yi Yang, Wan-Hsueh Cheng, Ting-Yang Yen, Zhicong Luo, Xin-Hong Qian, Zhi-Xin Chen, T. Lin, Wei-Hong Chen, Wei-Ming Chen, Sheng-Fu Liang, Fu-Zen Shaw, Cheng-Siu Chang, F. Shih, Y. Hsin, Chen-Yi Lee, M. Ker, Chung-Yu Wu
{"title":"A fully integrated closed-loop neuromodulation SoC with wireless power and bi-directional data telemetry for real-time human epileptic seizure control","authors":"Cheng-Hsiang Cheng, Ping-Yuan Tsai, Tzu-Yi Yang, Wan-Hsueh Cheng, Ting-Yang Yen, Zhicong Luo, Xin-Hong Qian, Zhi-Xin Chen, T. Lin, Wei-Hong Chen, Wei-Ming Chen, Sheng-Fu Liang, Fu-Zen Shaw, Cheng-Siu Chang, F. Shih, Y. Hsin, Chen-Yi Lee, M. Ker, Chung-Yu Wu","doi":"10.23919/VLSIC.2017.8008541","DOIUrl":null,"url":null,"abstract":"This paper presents a 16-channel closed-loop neuromodulation SoC for human seizure control. The SoC includes a 16-ch signal acquisition unit, a bio-signal processor, a 16-ch adaptive stimulator, and wireless telemetry. The signal acquisition unit achieves 3.78 NEF and shares electrodes with stimulator. The seizure detection latency is 0.76s and delivered 0.5–3mA biphasic current stimulation. The SoC is powered wirelessly and bidirectional data telemetry is realized through the same pair of coils in 13.56MHz.","PeriodicalId":176340,"journal":{"name":"2017 Symposium on VLSI Circuits","volume":"12 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2017-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"20","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"2017 Symposium on VLSI Circuits","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.23919/VLSIC.2017.8008541","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 20
Abstract
This paper presents a 16-channel closed-loop neuromodulation SoC for human seizure control. The SoC includes a 16-ch signal acquisition unit, a bio-signal processor, a 16-ch adaptive stimulator, and wireless telemetry. The signal acquisition unit achieves 3.78 NEF and shares electrodes with stimulator. The seizure detection latency is 0.76s and delivered 0.5–3mA biphasic current stimulation. The SoC is powered wirelessly and bidirectional data telemetry is realized through the same pair of coils in 13.56MHz.