Assessment of Antibiotic use in Pregnant Women in a Tertiary care Teaching Hospital – A Cross Sectional Observational Study

Rahul Sabbu, Anienye Prince, Doddaya Hiremath
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Abstract

During pregnancy, most women are at risk for respiratory tract infections (RTIs), urinary tract infections (UTIs), and ear, nose, and throat infections. Antimicrobials are the most commonly given medications to treat acquired illnesses during this time. This study aimed to assess antibiotic use in pregnant women in a tertiary care teaching hospital. The present study was a cross- sectional prospective observational study and was conducted for three months in a tertiary care health centre in North Karnataka with 57 participants.All case records of pregnant women who use antibiotics admitted to Obstetrics and Gynecology department and pregnant women with more than 18 years of age were included in the study. Out of 57 participants, 40.3% of them were belonging to the age category of 19-23 years of age, followed by 33.3% in 24-28 years. Most prevalent infections which required antimicrobials prescription were UTIs (36.82%), followed by Gastroenteritis (17.54%) and Pyrexia (14.03%). Majority of the antimicrobials prescribed were from Betalactams (40.34%), followed by Nitrofuranes (29.82%). To assist in making prescribing decisions for pregnant women, health care professionals should examine the teratogenic and toxic risk profiles of antibiotics. These could be especially significant if anti- infective countermeasures are needed to safeguard the health, safety, and survival of people who have been exposed to pathogenic bacteriologic agents as a result of bioterrorism. Keywords: Antimicrobials, pregnancy, teratogenic effect, urinary tract infections
三级护理教学医院孕妇抗生素使用评估——一项横断面观察研究
在怀孕期间,大多数女性都有呼吸道感染(RTIs)、尿路感染(uti)和耳鼻喉感染的风险。在此期间,抗微生物药物是治疗获得性疾病最常用的药物。本研究旨在评估三级护理教学医院孕妇抗生素使用情况。本研究是一项横断面前瞻性观察研究,在北卡纳塔克邦的一家三级保健中心进行了为期三个月的研究,共有57名参与者。所有在妇产科住院的使用抗生素的孕妇和18岁以上的孕妇的病例记录都被纳入研究。57名参与者中,年龄在19-23岁的占40.3%,24-28岁的占33.3%。最常见的抗菌药物处方感染为尿路感染(36.82%),其次为胃肠炎(17.54%)和发热(14.03%)。使用的抗菌剂以β他坦类(40.34%)最多,其次是硝基呋喃类(29.82%)。为了帮助孕妇作出处方决定,卫生保健专业人员应检查抗生素的致畸性和毒性风险概况。如果需要采取抗感染对策,以保障因生物恐怖主义而接触致病性细菌制剂的人的健康、安全和生存,这些措施可能特别重要。关键词:抗菌药物,妊娠,致畸效应,尿路感染
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