Possible menstrual cycle changes after COVID 19 vaccination a questionnaire-based study among vaccinated women

Abstract

On January 21 2021, India granted emergency use authorization to Covishield (non-replicating adenovirus vaccine) and Covaxin (viral inactivating vaccination). Reports till 02 Jan 2023 suggest a cumulative total of 2,20,10,77,192 vaccination doses administered among the Indian Population. A sore arm, fever, and myalgia are the most common side effects of covid-19 immunization, according to the UK's Medicines and Healthcare Products Regulatory Agency (MHRA). COVID-19 vaccination has not been shown to negatively affect fertility in any of the clinical trials. However, patients who have encountered alterations in their menstrual cycle and bleeding patterns quickly after vaccination are increasingly approaching primary care providers and reproductive health professionals Therefore, our study aims in collecting data from pre-menopausal, vaccinated women regarding alterations in their menstrual cycle post COVID-19 Vaccination through a self-administered pre-validated Questionnaire. Our study implies that almost 77.9% of the study participants did not observe any menstrual changes while 23.1% of the reported abnormal menstruation cycles which included delayed cycles, early cycles, less bleeding than normal and change in blood color. Our study’s conclusion highlights the need for larger studies to identify the possibility for a relationship to exist between COVID 19 Vaccination and Menstrual cycle.