Serum Electrolytes and Oxygen Saturation in Acute Exacerbation of Chronic Obstructive Pulmonary Disease Patients

R. S, Das Br
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Abstract

Background: Chronic obstructive pulmonary disease, or COPD, refers to a group of diseases that cause airflow blockage and breathing-related problems. It includes emphysema and chronic bronchitis. Patients with COPD are at increased risk of developing heart disease, lung cancer and a variety of other conditions. Although COPD is mostly a chronic disease, a substantial number of patients experience exacerbations that are related to a significantly worse survival result, especially with abnormal serum electrolyte level. Objectives: The aim of this study is to assess the Serum Electrolytes and Oxygen saturation in acute exacerbation of chronic obstructive pulmonary disease patients. Methods: This is an observational study. The study was carried out in the admitted patient’s Department of Medicine, Netrokona Medical College and hospital, Bangladesh. The duration of the study from October 2019 to March 2021. Results: This study shows that the according to age of 120 Patients aged 40 to 69 years. Here according to Age distribution, 6(5%) were <40 years, 8(6.66%) were 40- 49 years, 21(17.5%) were 50-59 years, 48(40%) were 60-69 years and 37 (30.83%) were ≥ 70 years. Distribution of the study according to sex of 120 Patients aged 40 to 69 years. According to gender 102(85%) were Male, 18(15%) were Female. According to Parameter, the Mean±SD of Serum Sodium, Serum Potassium, O2 Flow (L/min), pH, PaCO2 (mmHg), HCO3 (mmol/L), SpO2 (%) and Respiratory Rate (Breaths/min) were 131±5.07, 3.31±0.33, 0.6±0.4, 7.43±0.02, 40±4, 27±2, 90±1.2 and 22±3 respectfully. Conclusions: The levels of parameters should be measured and corrected during AECOPD treatment to decrease mortality and the correct use of supplemental oxygen therapy during exacerbations of COPD is an impor¬tant factor that can strongly influence outcomes.
慢性阻塞性肺疾病急性加重期患者的血清电解质和血氧饱和度
背景:慢性阻塞性肺疾病(COPD)是指引起气流阻塞和呼吸相关问题的一组疾病。它包括肺气肿和慢性支气管炎。慢性阻塞性肺病患者患心脏病、肺癌和其他各种疾病的风险增加。虽然COPD主要是一种慢性疾病,但相当数量的患者会经历与生存结果显着恶化相关的恶化,特别是血清电解质水平异常。目的:本研究的目的是评估慢性阻塞性肺疾病急性加重期患者血清电解质和血氧饱和度。方法:观察性研究。这项研究是在孟加拉国Netrokona医学院和医院的住院病人医学部进行的。研究时间为2019年10月至2021年3月。结果:本研究显示120例患者年龄在40 ~ 69岁。年龄分布:<40岁6例(5%),40 ~ 49岁8例(6.66%),50 ~ 59岁21例(17.5%),60 ~ 69岁48例(40%),≥70岁37例(30.83%)。120例40 ~ 69岁患者按性别分布。按性别分,男性102例(85%),女性18例(15%)。根据参数,血清钠、血清钾、血氧流量(L/min)、pH、PaCO2 (mmHg)、HCO3 (mmol/L)、SpO2(%)、呼吸频率(呼吸次数/min)的平均值±SD分别为131±5.07、3.31±0.33、0.6±0.4、7.43±0.02、40±4、27±2、90±1.2和22±3。结论:在AECOPD治疗过程中应测量和纠正参数水平,以降低死亡率,COPD加重期正确使用补充氧治疗是影响预后的重要因素。
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