Zoonotic Tuberculosis: A Concern and Strategies to Combat

Ravi N. Teppawar, Sandeep P. Chaudhari, Shilpa L. Moon, Shilpshri V. Shinde, Wiqar A. Khan, Archana R. Patil
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引用次数: 20

Abstract

Mycobacterium bovis is the main causal agent of bovine tuberculosis that causes zoonotic tuberculosis in humans. The most common routes of transmission of the agent to human are airborne transmission, consumption of unpasteurized milk, direct contact with infected animals or untreated animal products. Conventional diagnostic methods in com- bination with modern molecular and immunological techniques should be used for early and accurate diagnosis of the disease. Some of the challenges to tackle and eradicate zoonotic TB in developing countries are having many hosts, absence of early diagnosis, presence of other acute diseases, being economically unable to implement control strate- gies, and other social and cultural issues. Usually treatment is not recommended in animals but vaccination is carried out in some countries as a preventive measure. Due to the grave consequences of M. bovis infection on animal and human health, it is necessary to introduce accurate control measures to reduce the risk of disease in human and animal populations. Proper food hygiene practices, slaughter of the affected animals in developed countries, and segregation of the suspected animals in developing countries along with stronger intersectoral collaboration between the veterinary and medical professions are important for the control of the disease.
人畜共患结核病:关注与防治策略
牛分枝杆菌是引起人类人畜共患结核病的牛结核病的主要病原体。人类最常见的传播途径是空气传播、饮用未经巴氏消毒的牛奶、直接接触受感染的动物或未经处理的动物产品。常规诊断方法应与现代分子和免疫学技术相结合,以早期准确诊断本病。在发展中国家应对和根除人畜共患结核病的一些挑战包括:宿主众多、缺乏早期诊断、存在其他急性疾病、经济上无法实施控制战略以及其他社会和文化问题。通常不建议对动物进行治疗,但一些国家将接种疫苗作为预防措施。由于牛支原体感染对动物和人类健康造成严重后果,有必要采取准确的控制措施,以减少人类和动物群体中的疾病风险。在发达国家采取适当的食品卫生做法,屠宰受影响的动物,在发展中国家隔离疑似动物,以及加强兽医和医疗专业之间的部门间合作,对控制该疾病非常重要。
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