CRUCUMIN ROLE IN BREAST CANCER TREATMENT

Abstract

One of the most common forms of malignant tumors is breast cancer worldwide, has a high fatality rate. The development of novel chemicals and technological advancements that will allow the adoption of safer and more efficient therapeutic techniques has received a lot of attention in order to address this problem. In order to maximize tumor growth inhibition and reduce side effects, it has been suggested that combining nanoparticles with well-known anticancer agents including compounds derived from plants, like curcumin is an effective strategy. Curcumin exploits a complex network of molecular signals, including the proliferative, ER, and HER2 pathways, to exert its anticancer actions. According to experimental results, curcumin controls genes associated to cell phase, microRNA, and apoptosis in breast cancer cells.