Proteus vulgaris Response to Various Antibacterial Agents

Arwa Saud Abbas, Hafiz Shahzad Muzammil, Hina Asif
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Abstract

Proteus vulgaris is commonly associated with urinary tract infections, wound infections and sepsis. The ability of microorganisms to resist antibiotic actions is referred to as antibiotic resistance. Objective: To compare the antibacterial effects of various medications on clinical isolates of P. vulgaris was the goal. Methods: Over the course of a year, 1000 samples were collected in a cross-sectional study at a hospital in Lahore, Pakistan. The Kirby-Bauer disc diffusion technique was used to test for antibiotic susceptibility. Results: It was determined that the most efficient antibacterial medicines against P. vulgaris. were Imipenem, Gentamycin, Amikacin, Augmentin, Linezolid, Levofloxacin, Ceftazidime, Norfloxacine, and Cefazolin. On the other hand, Meropenem, Cephalothin, Rifampicin, Cefoxitin, and Ampicillin had little effect on Proteus vulgaris. Conclusions: The study emphasizes the significance of preventative measures, such as responsible antibiotic use, the development of novel treatments, and the application of infection control techniques in healthcare settings, to effectively manage and prevent the spread of resistance. Antibiotic resistance in P. vulgaris is becoming a growing cause for concern.
寻常变形杆菌对各种抗菌剂的反应
寻常变形杆菌通常与尿路感染、伤口感染和败血症有关。微生物抵抗抗生素作用的能力被称为抗生素耐药性。目的:比较不同药物对临床分离的寻常假单胞菌的抑菌效果。方法:在巴基斯坦拉合尔一家医院的一年中,在横断面研究中收集了1000个样本。采用Kirby-Bauer圆盘扩散技术检测抗生素敏感性。结果:确定了对寻常假单胞菌最有效的抗菌药物。分别是亚胺培南、庆大霉素、阿米卡星、奥格门汀、利奈唑胺、左氧氟沙星、头孢他啶、诺氟沙星和头孢唑林。美罗培南、头孢菌素、利福平、头孢西丁、氨苄西林对寻常型变形杆菌的影响较小。结论:该研究强调了预防措施的重要性,如负责任地使用抗生素,开发新的治疗方法,以及在卫生保健环境中应用感染控制技术,以有效管理和防止耐药性的传播。寻常假单胞菌的抗生素耐药性日益引起人们的关注。
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