The Course of Alcoholic Cirrhosis of The Liver in a Patient with COVID-19

E. Kudashkina, L. Ilchenko, I. Fedorov
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Abstract

This article presents the features of the course of liver cirrhosis (LC) in a patient with a new coronavirus infection. The patient had no specific respiratory symptoms of COVID-19 (CoronaVirus Disease 2019), and the reason for outpatient examination for SARS-CoV-2 (severe acute respiratory syndrome coronavirus) RNA was the presence of these symptoms in relatives. Previously, patient E. had been undergoing in-patient examination and treatment for abdomen volume build-up against the background of prolonged alcoholization, and was diagnosed with alcoholic class B LC according to Child-Pugh classification. Conservative therapy was administered, and the patient was discharged with regression of ascites. Within a week after SARS-CoV-2 identification, patient E. showed signs of LC decompensation in the form of increasing abdominal volume, which required repeated inpatient treatment, during which portal vein thrombosis (PVT) and progression of chronic liver disease (CLD) in the post-coid period were revealed. Literature data on 30-day mortality in patients with LC against COVID-19 background are presented, as well as my own observations on the example of 580 case histories. Complications of new coronavirus infection in patients with CLD, methods of their correction are considered here. This observation demonstrates the social significance of the problem of COVID-19 incidence in patients with LC, the necessity for screening for COVID-19 in case of the presence of decompensation episodes, as well as active prevention of infection in these patients.
1例新冠肺炎患者酒精性肝硬化的病程分析
本文介绍了1例新型冠状病毒感染患者肝硬化(LC)病程的特点。患者无特定的COVID-19(冠状病毒病2019)呼吸道症状,门诊检查SARS-CoV-2(严重急性呼吸综合征冠状病毒)RNA的原因是亲属存在这些症状。此前,患者e因长期酒精中毒背景下腹部体积增大而接受住院检查和治疗,并根据Child-Pugh分类诊断为酒精性B级LC。给予保守治疗,患者因腹水消退出院。在SARS-CoV-2鉴定后一周内,患者e出现LC失代偿的迹象,表现为腹部体积增加,需要反复住院治疗,期间发现门静脉血栓形成(PVT)和慢性肝病(CLD)的进展。本文介绍了COVID-19背景下LC患者30天死亡率的文献数据,以及我自己对580例病史的观察。本文讨论了CLD患者新型冠状病毒感染的并发症及其纠正方法。这一观察结果说明了LC患者COVID-19发病率问题的社会意义,以及出现失代偿发作时筛查COVID-19的必要性,以及在LC患者中积极预防感染的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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