Transforming Growth Factor Beta 1 in the Ascitic Fluid as Predictor for Spontaneous Bacterial Peritonitis in Cirrhotic Patients due to Hepatitis C Virus infection in Suez Canal University Hospital
{"title":"Transforming Growth Factor Beta 1 in the Ascitic Fluid as Predictor for Spontaneous Bacterial Peritonitis in Cirrhotic Patients due to Hepatitis C Virus infection in Suez Canal University Hospital","authors":"Samar Abd-Raboh, M. Sheir, F. Attia, A. Salem","doi":"10.21608/aeji.2022.144030.1229","DOIUrl":null,"url":null,"abstract":"concentrations. The work was carried out in the Internal Medicine Department of Suez Canal University Hospital. Results: TGF-β1 levels in the ascitic fluid were correlated significantly with ascitic fluid PMNLs and significantly higher in patients with SBP than non-SBP (P<0.001), with the best cutoff value for the detection of SBP of 151.5 ng/ml with a sensitivity of 100 % and a specificity of 100%. Conclusion: Elevated ascitic fluid TGF-β1 levels in cirrhotic patients are a diagnostic and reliable marker for the detection of SBP.","PeriodicalId":261891,"journal":{"name":"Afro-Egyptian Journal of Infectious and Endemic Diseases","volume":"43 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Afro-Egyptian Journal of Infectious and Endemic Diseases","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21608/aeji.2022.144030.1229","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
concentrations. The work was carried out in the Internal Medicine Department of Suez Canal University Hospital. Results: TGF-β1 levels in the ascitic fluid were correlated significantly with ascitic fluid PMNLs and significantly higher in patients with SBP than non-SBP (P<0.001), with the best cutoff value for the detection of SBP of 151.5 ng/ml with a sensitivity of 100 % and a specificity of 100%. Conclusion: Elevated ascitic fluid TGF-β1 levels in cirrhotic patients are a diagnostic and reliable marker for the detection of SBP.