Role of medicinal plants against Alzheimer’s disease

A. Roy
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引用次数: 32

Abstract

Neurodegenerative ailments are heterogeneous group of genetic disorders that are indicated by loss of neuronal structure, function and generally lead to neuronal loss. These ailments may result directly from particular neuronal population degeneration or indirectly from changes in glial support cells. These kinds of ailments are characterized by an abnormal proteins accumulation or other biological materials accumulation within or outside the neurons. These aggregations take different structures and result in neurofabrillary tangles in Alzheimer’s disease, Lewy bodies in Parkinson’s disease, glycogen and polyglucosan bodies in Lafora disease. Alzheimer’s disease is thought to be in responsible of 60% of all mental disorder in moderately aged or older adults1 and influencing in excess of 5 million Americans, a number assessed to increment to 7.7million by 2030.
药用植物抗阿尔茨海默病的作用
神经退行性疾病是一类异质性遗传疾病,表现为神经元结构和功能的丧失,通常导致神经元的丧失。这些疾病可能直接由特定神经元群的退化或间接由神经胶质支持细胞的变化引起。这类疾病的特征是异常的蛋白质积累或其他生物物质在神经元内外的积累。这些聚集具有不同的结构,导致阿尔茨海默病的神经纤维缠结,帕金森病的路易小体,拉福拉病的糖原和多葡聚糖小体。阿尔茨海默病被认为是导致60%的中老年或老年人精神障碍的原因,影响了500多万美国人,据估计,到2030年,这一数字将增加到770万。
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