A Systematic Review on Drug Interaction Prediction Using Various Methods to Reduce Adverse Effects

G. L. Swathi Mirthika, B. Sivakumar
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Abstract

Interaction prediction between the drugs is a preeminent task. Drug - drug interaction (DDI) causes serious effects to human life. The adverse effect can result in death when the interaction is not known. Predicting all DDI is a challenging mission as it requires much time. Health care professionals and care givers may not be aware of all potential drug interactions. Many studies have been carried out to predict the DDI in meticulous way. Drug banks play the major role in providing information about the drugs; through drug banks we could predict the adverse effect while using two or more drugs together and can avoid the adverse reaction caused by DDI. In this article, the authors have compared different approaches used for predicting the interactions, analyzed with the methods and a comparison is provided for understanding the methods used in each research work.
用各种方法预测药物相互作用以减少不良反应的系统综述
预测药物之间的相互作用是一项重要的任务。药物-药物相互作用(DDI)对人类生命造成严重影响。在相互作用未知的情况下,不良影响可能导致死亡。预测所有DDI是一项具有挑战性的任务,因为它需要大量的时间。卫生保健专业人员和护理人员可能不知道所有潜在的药物相互作用。许多研究都对DDI进行了细致的预测。药品银行在提供药品信息方面发挥着重要作用;通过药物库可以预测两种或两种以上药物同时使用时的不良反应,避免DDI引起的不良反应。在本文中,作者比较了用于预测相互作用的不同方法,对这些方法进行了分析,并提供了一个比较,以了解每个研究工作中使用的方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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