GAMBARAN KADAR ASAM URAT PADA PASIEN TUBERKULOSIS PARU SENSITIF OBAT SETELAH PENGOBATAN FASE INTENSIF DI PUSKESMAS KECAMATAN KRAMAT JATI Nicolaus Sri Widada, Ayuningtias Wulandari

Abstract

Tuberculosis treatment that using multi-drugs principle with a long-time treatment period often causes side effects. One of the side effects is increasing of uric acid levels. Pyrazinamide and ethambutol are medicines that increase uric acid levels in the body. The purpose of this research was to determine characteristics drugssensitive pulmonary TB patients based on gender and age, to determine the average of urid acid levels after intensive phase treatment and to determine percentage of the drugs-sensitive pulmonary TB patients that have increasing uric acid levels at the Kramat Jati District Health Center. The type of this study is quantitative descriptive with cross sectional data collection techniques and consecutive sampling technique. The results of the statistical distribution of the mean blood uric acid levels in drug-sensitive pulmonary TB patients were 7.4 ± 2.84 mg / dl (mean ± SD) with the lowest level of 3.5 mg / dl and the highest level of 11.8 mg / dl. If it grouped by reference value, data obtained from drug-sensitive pulmonary TB patients with uric acid levels increased by 54.5%with the highest proportion in the age group ≥55 years (100%). Suggestions for pulmonary TB patients who are undergoing anti tuberculosis drugs (ATDs) therapy are expected to reduce the intake of high-purine foods and routinely do medical check-up.