Performance of Rapid Diagnosis Technique (RDT) in Screening Malaria Among Patients of Selected Health Facilities in Ardo-Kola Local Government Area, Taraba State

Obiorah Sylvester Chibuozor, Elkanah Obadiah Sambo, Onyeuku Okechukwu Chinwe, Elkanah Deborah Sambo, Agbo Oche Joseph, Ayibatonye Lemmy Orutugu
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Abstract

Malaria infection is one of the most common disease of public health importance afflicting millions of people in sub-Saharan Africa. Malaria diagnosis and surveillance rely predominantly on rapid diagnostic tests (RDTs). This study investigated the performance of Rapid Diagnostic Test (RDT) against microscopy of stained blood for Plasmodium falciparum of patients attending some Primary Health Centres in Ardo-Kola LGA, Taraba State. Five hundred and eighty five (585) blood samples were collected and examined for Plasmodium falciparum on the microscope. Rapid Diagnostic Tests were also used for examination. The overall result showed a prevalence of 446 (76.23%). The infection found female, 199 (82.23%) to be more exposed to malaria than male, 247 (72.01%) with no significant difference (χ 2 =4.381; P≥0.05). With regards to age, females aged ≥51 years were more infected than other age groups, while male aged 21-30 years were more infected with malaria than the other age groups. There was no significant difference with malaria infection between the age groups (χ 2 =2.207; P≥0.05). The performance of RDTs against microscopy showed that RDT used had a sensitivity of 66.91% and specificity of 58.52%. The positive predictive value of 33.45% and negative predictive value of 85.02% were found for the RDT used. The present study demonstrated that RDTs can act as diagnostic tool to manage malaria in resource poor settings with limited, access to expert microscopy as they are easy to use and perform better than microscopy. It is recommended that malaria Rapid Diagnosis Tests can be used in endemic areas in Nigeria.
快速诊断技术(RDT)在塔拉巴州Ardo-Kola地方政府地区选定卫生机构患者中筛查疟疾的效果
疟疾感染是影响撒哈拉以南非洲数百万人的最常见公共卫生疾病之一。疟疾诊断和监测主要依靠快速诊断检测。本研究调查了在塔拉巴州Ardo-Kola LGA的一些初级卫生中心就诊的患者的快速诊断试验(RDT)对染色血液显微镜检测恶性疟原虫的性能。收集了585份血样,在显微镜下检查了恶性疟原虫。快速诊断试验也用于检查。总体结果为446例(76.23%)。感染病例中,女性199例(82.23%)高于男性247例(72.01%),差异无统计学意义(χ 2 =4.381;P≥0.05)。就年龄而言,年龄≥51岁的女性感染疟疾的比例高于其他年龄组,而21-30岁的男性感染疟疾的比例高于其他年龄组。各年龄组间疟疾感染情况差异无统计学意义(χ 2 =2.207;P≥0.05)。显微检测结果显示,RDT的敏感性为66.91%,特异性为58.52%。RDT的阳性预测值为33.45%,阴性预测值为85.02%。目前的研究表明,RDTs可以作为一种诊断工具,在资源匮乏、获得专家显微镜的机会有限的环境中管理疟疾,因为它们易于使用,而且比显微镜更好。建议在尼日利亚流行地区使用疟疾快速诊断检测。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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