Towards a biodegradable, electro-active nerve repair conduit

Abstract

An approach to applying alternating electric fields to regenerating neurons from a wirelessly powered nerve repair conduit is outlined here. An electrical stimulation waveform capable of controlling neuronal growth is demonstrated with hybrid stimulation modules that consist of mechanical and electrical guidance cues. An inductive powering system is used to deliver this stimulation signal to a biodegradable electro-active substrate, validating it as a potential implant device. A passive impedance sensor, designed to chart cell growth within an implant is then discussed.