Endovascular Occlusion in Combined Treatment of Arteriovenous Erectile Disfunction

K. A. Burdin
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Abstract

BACKGROUND: The vasculogenic nature of the erectile dysfunction (ED) prevails over other causes and accounts for 70%, of which 30% is arteriogenic, 20% to 40% is venogenic, and 30% is mixed arteriovenous ED. The main importance of shock wave therapy (SWT) in the treatment of ED is a complex positive effect on the blood supply of the penis. However, there is not enough information in the literature about the use of SWT in patients with arteriovenous ED, which determines the relevance of research in this direction. AIM: To evaluate the results of combined treatment (SWT and endovascular embolization of the deep dorsal vein (DDV) of the penis) in patients with arteriovenous ED. MATERIALS AND METHODS: In the Federal State Research Center of the Federal Medical and Biomedical Agency named after AI Burnazyan of Russia 45 patients aged 26 to 45 years (35.5 ± 9.5) years with a confirmed clinical diagnosis of arteriovenous ED, who underwent combined treatment were examined. The treatment was performed in 2 stages: stage I included endovascular embolization of the dorsal penile vein; stage II consisted of SWT with the use of BTL-6000 SWT TOPLINE device (BTL Corporate) in 2 weeks after surgical treatment. The condition of patients was assessed before treatment and 1 and 12 months after it. The assessment was based on the data of the questionnaire of the International Index of Erectile Function, fifth revision (IIEF-5), and the Erection Rigidity Scale (ESR), as well as instrumental diagnostic methods: computer dynamic cavernosography and pharmacodoplerography. RESULTS: An improvement of blood flow velocity parameters, a positive dynamic according to IIEF-5 and SER in 1 year following treatment. CONCLUSIONS: The use of endovascular occlusion in combination with SWT is the correct method of treatment for arteriovenous ED, but still requires further study.
血管内闭塞联合治疗动静脉性勃起功能障碍
背景:勃起功能障碍(ED)的血管源性高于其他原因,占70%,其中30%为动脉源性,20%至40%为静脉源性,30%为混合动静脉性ED。冲击波治疗(SWT)在ED治疗中的主要作用是对阴茎血液供应的复杂积极作用。然而,关于在动静脉ED患者中使用SWT的文献信息不足,这决定了该方向研究的相关性。目的:评价SWT联合阴茎深背静脉(DDV)血管内栓塞治疗动静脉性ED的效果。材料与方法:在俄罗斯联邦医学和生物医学署(以AI Burnazyan命名)联邦国家研究中心,对45例26 ~ 45岁(35.5±9.5)岁临床确诊为动静脉性ED的患者进行联合治疗。治疗分2期进行:一期为阴茎背静脉血管内栓塞;二期包括在手术治疗后2周使用BTL-6000 SWT TOPLINE装置(BTL Corporate)进行SWT。分别于治疗前、治疗后1个月和12个月对患者进行病情评估。评估依据国际勃起功能指数第五版(IIEF-5)调查问卷和勃起刚性量表(ESR),以及计算机动态海脉管造影和药理学仪器诊断方法。结果:治疗后1年血流速度参数改善,IIEF-5和SER呈阳性动态。结论:血管内闭塞联合SWT是治疗动静脉ED的正确方法,但仍需进一步研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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