Recent advances in vaccines and therapeutics for Nipah virus

Abin V. Geevarghese, V. Christi
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Abstract

The Nipah virus (NiV) is a newly discovered zoonotic paramyxovirus that affects people and causes serious, frequently fatal respiratory and neurological conditions. Following an encephalitis outbreak among pig farmers in Malaysia and Singapore, the virus was initially identified, and subsequent outbreaks in Bangladesh or India took place virtually annually. Due to NiV’s high pathogenicity, the pandemic potential spread, and lack of licensed vaccines or therapeutics, research and development is needed to create highly sensitive and precise diagnostic tools, antivirals, and vaccines that will aid in preventing and controlling outbreak situations in the future.
尼帕病毒疫苗和治疗方法的最新进展
尼帕病毒是一种新发现的人畜共患副粘病毒,可影响人类并引起严重的、往往致命的呼吸道和神经系统疾病。在马来西亚和新加坡的养猪户中爆发脑炎后,最初确定了该病毒,随后在孟加拉国或印度几乎每年都发生疫情。由于NiV的高致病性、大流行的潜在传播以及缺乏许可的疫苗或治疗方法,需要进行研究和开发,以创造高度敏感和精确的诊断工具、抗病毒药物和疫苗,以帮助预防和控制未来的疫情。
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