Informational bioeffects Atlas of laser lesions (IBALL) – Developing an online database for clinicians and researchers

A. Peterson, Adam R. Boretsky, Mark A. Keppler, E. Gil, Aaron S. Engler, Oscar Garza, Matthew Macasadia, Jacob M. Rivera, G. Noojin, J. Bixler
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Abstract

Lasers are increasingly present in modern life. Applications have expanded across industrial processes, medical treatments, military use, and common consumer products. As the availability of laser technology continues to grow, safety concerns increase accordingly. Despite the availability of ocular laser injury data in literature, no single source existed to help clinicians identify and classify ocular laser injuries when they encountered them in clinical settings. The Informational Bioeffects Atlas of Laser Lesions (IBALL) program provides DoD clinicians and researchers a searchable electronic database of images to use when identifying laser damage based on various exposure parameters, lesion characteristics, and diagnostic imaging modalities. In addition to providing reference images of retinal laser injury across a wide lesion parameter space, longitudinal experimental data collection captured the dynamic tissue response for days or even weeks post-exposure. Analysis of laser lesion characteristics across multiple imaging modalities, such as fundus photography and Optical Coherence Tomography, also provided complementary views of the tissue to improve our understanding of the innate biological response to laser radiation. Finally, the database design included a flexible and scalable environment to accommodate a variety of imaging data formats and future the incorporation of new experimental data.Lasers are increasingly present in modern life. Applications have expanded across industrial processes, medical treatments, military use, and common consumer products. As the availability of laser technology continues to grow, safety concerns increase accordingly. Despite the availability of ocular laser injury data in literature, no single source existed to help clinicians identify and classify ocular laser injuries when they encountered them in clinical settings. The Informational Bioeffects Atlas of Laser Lesions (IBALL) program provides DoD clinicians and researchers a searchable electronic database of images to use when identifying laser damage based on various exposure parameters, lesion characteristics, and diagnostic imaging modalities. In addition to providing reference images of retinal laser injury across a wide lesion parameter space, longitudinal experimental data collection captured the dynamic tissue response for days or even weeks post-exposure. Analysis of laser lesion characteristics acr...
激光病变信息生物效应图谱(IBALL)——为临床医生和研究人员开发一个在线数据库
激光越来越多地出现在现代生活中。应用已扩展到工业过程、医疗、军事用途和普通消费品。随着激光技术的不断发展,安全问题也随之增加。尽管文献中有眼部激光损伤数据,但当临床医生在临床上遇到眼部激光损伤时,没有单一的来源可以帮助他们识别和分类。激光病变信息生物效应图谱(IBALL)项目为国防部临床医生和研究人员提供了一个可搜索的图像电子数据库,用于根据各种暴露参数、病变特征和诊断成像方式识别激光损伤。除了提供跨广泛病变参数空间的视网膜激光损伤的参考图像外,纵向实验数据收集还捕获了暴露后数天甚至数周的动态组织反应。通过多种成像方式(如眼底摄影和光学相干断层扫描)对激光病变特征进行分析,也提供了组织的补充视图,以提高我们对激光辐射的先天生物反应的理解。最后,数据库设计包括一个灵活和可扩展的环境,以适应各种成像数据格式和未来新的实验数据的合并。激光越来越多地出现在现代生活中。应用已扩展到工业过程、医疗、军事用途和普通消费品。随着激光技术的不断发展,安全问题也随之增加。尽管文献中有眼部激光损伤数据,但当临床医生在临床上遇到眼部激光损伤时,没有单一的来源可以帮助他们识别和分类。激光病变信息生物效应图谱(IBALL)项目为国防部临床医生和研究人员提供了一个可搜索的图像电子数据库,用于根据各种暴露参数、病变特征和诊断成像方式识别激光损伤。除了提供跨广泛病变参数空间的视网膜激光损伤的参考图像外,纵向实验数据收集还捕获了暴露后数天甚至数周的动态组织反应。激光损伤特征分析…
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