Investigation of the ultrastructure of DNA-synthesizing cells of a focus of aseptic inflammation.

Abstract

The ultrastructure of cells of a focus of aseptic inflammation, synthesizing DNA (incorporating H3-thymidine) was studied with the aid of a combination of methods of light autoradiography and plane-parallel embedding. It was shown that these cells have the ultrastructure specific for collagen-synthesizing cells (fibroblasts): a well-developed granular endoplasmic reticulum with a large number of polyribosomes, an extensive Golgi complex, a characteristic structure of the mitochondria, and a large number of cytoplasmic microfibers. Collagen fibers are detected on the surface of the cells.