Study of the specificity of the action of adhesive factors isolated from the liver and lungs of adult mice and rats.

Abstract

Adhesive factors (AF), enhancing the cohesion of cells in liver and lung tissues, were isolated from the liquid obtained in the incubation of pieces of liver and lung of adult mice and rats in calcium-free salt solution. The action of AF was evaluated according to their influence on the strength of cohesion of the cells in the lung and liver, measured with a micromanipulator, and according to the number of cells isolated from the liver by dispersion. The presence of tissue specificity and the absence of species specificity of the action of AF on the tissues of adult animals was demonstrated.