Inferior Vena Cava Collapsibility Index and the Risk of Contrast-Induced Nephropathy in Patients Undergoing Coronary Angiography

Abstract

Introduction: The present study aims to investigate the association between contrast-induced nephropathy (CIN) and inferior vena cava collapsibility index (IVC-CI) measured via echocardiography to estimate intravascular volume. Patients and Methods: A total of 100 patients were referred to coronary angiography (CAG). On the day of admission, blood samples were collected, and an echocardiographic evaluation was performed to estimate IVC-CI immediately before CAG. IVC-CI ratios were stratified into three groups (low, mid, high) (<50%, 50-75%, >75%). Creatinine was assessed again at 48 hours following the CAG procedure. The difference between baseline serum creatinine and serum creatinine at 48 hours was calculated as ΔCrea while the difference in GFR was calculated as ΔGFR. Biochemical parameters and CIN ratios were compared between all groups. Results: There were no differences across the groups in terms of procedural characteristics, preprocedural lab parameters, and concomitant medication. ΔCreatinine, ΔGFR, and the incidence of CIN were significantly higher in the high IVC-CI group. Conclusion: Post-procedure incidence of CIN, ΔGFR, and Δcreatinine compared to the pre-procedure values were higher in the high IVC-CI group.