Study of the antidepressant properties of some plants

Abstract

Currently, in the world, the COVID-19 pandemic has led to an increase in the level of mental disorders in the population due to self-isolation, the imposed quarantine regime, and an alarming media environment. Therefore, a very important world task today is the search and development of drugs that have psychotropic activity, reduce anxiety and aggression without negatively affecting psychomotor and cognitive functions, capable of preventing the development of mental disorders in the population. These products are, first of all, products of natural origin. This article presents the results of a study of the antidepressant effect in plants of the genus Hedysarum (roots of H. theinum Krasnob., roots of H. neglectum Ledeb., herbs H. alpinum L.) and of the genus Garcinia (pericarp of the fruit of G. mangostana L.). A pronounced anti- anxiety effect of herbal extracts and, at the same time, a complete absence of a depriming effect is shown, which justifies the possibility of using these drugs for the prevention and correction of mental disorders associated with aggression, an increased level of anxiety, and impaired cognitive functions. © 2021 Author(s).