SÍNDROME DOS OVÁRIOS POLICÍSTICOS: uma revisão

Débora Regina Gomes Vilela, Andressa Morgenstern Santos, Gabriel Henrique Roewer, Marília Bassani Mendes, Thais Cristine Souza Silva, Vanessa Regina Maciel Uzan de Moraes
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Abstract

Stein-Leventhal syndrome, currently known as polycystic ovary syndrome (PCOS), is a common ovulatory disorder among women, affecting approximately 6-19% of the female population who are in menopause. It is characterized by presenting hyperandrogenic, reproductive and metabolic alterations. Although its etiology is complex, the relationship between genetic predisposition and environmental factors in the pathology has been proven. Furthermore, the pathophysiologic mechanisms that lead to PCOS are multifactorial, and it is believed to be a complex multigenic disorder, including hypothalamic-pituitary axis abnormalities, steroidogenesis, and insulin resistance. Treatment for PCOS aims to reduce the manifestations of hyperandrogenism, regularize menstrual cycles and correct metabolic changes. This is a systematic literature review, in which a survey of 47 articles was carried out, of which 16 articles were used. Inclusion criteria were articles dealing with polycystic ovary syndrome, in Portuguese and English. At the beginning of the research, 47 articles were selected that fit the keywords, of which 31 (65.9%) were excluded, which did not address the polycystic ovary syndrome. This paper reports the definition of PCOS, its causes, pathophysiological mechanisms and diagnostic criteria. In addition, this article on the treatment of PCOS exposes that the practice of physical exercise, together with nutritional guidance, are important for the improvement of the symptoms of the syndrome. FINAL: The importance of early diagnosis and treatment is emphasized, in order to prevent metabolic, hyperandrogenic and reproductive changes that affect the quality of life of patients with PCOS.
多囊卵巢综合征:综述
Stein-Leventhal综合征,目前称为多囊卵巢综合征(PCOS),是一种常见的女性排卵障碍,影响约6-19%的绝经期女性人口。它的特点是表现出高雄激素,生殖和代谢改变。虽然其病因复杂,但病理上遗传易感性与环境因素之间的关系已得到证实。此外,导致多囊卵巢综合征的病理生理机制是多因素的,它被认为是一种复杂的多基因疾病,包括下丘脑-垂体轴异常、类固醇生成和胰岛素抵抗。治疗多囊卵巢综合征的目的是减少高雄激素症的表现,调节月经周期和纠正代谢变化。这是一个系统的文献综述,共调查了47篇文章,其中使用了16篇文章。纳入标准为葡萄牙语和英语的多囊卵巢综合征相关文章。在研究开始时,选择了47篇符合关键词的文章,其中31篇(65.9%)没有涉及多囊卵巢综合征,被排除。本文就多囊卵巢综合征的定义、病因、病理生理机制及诊断标准作一综述。此外,这篇关于多囊卵巢综合征治疗的文章揭示了体育锻炼的实践,加上营养指导,对改善该综合征的症状很重要。最后:强调早期诊断和治疗的重要性,以防止影响PCOS患者生活质量的代谢、高雄激素和生殖改变。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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