Axial centrifugal filtration — A novel approach for rapid bacterial concentration from a large volume

Abstract

A novel approach for filtration on a centrifugal microfluidic platform is presented for the first time. This approach is intended to concentrate bacteria from a large volume. In axial centrifugal filtration the filter is oriented perpendicular to the axis of rotation. This feature allows for integration of dead-end filtration while the filter cake is continuously removed from the filter by centrifugation. This prevents clogging of the filter. Furthermore, a continuous sample feed enables processing of large samples on one disk. Especially for analyzing drinking water large volumes have to be processed and solutions for rapid bacterial concentration are highly appreciated.