Giant Verruca Vulgaris-Rare Presentation

Abstract

Common wart is the most frequent clinical lesion caused by human papillomaviruses (HPVs). Giant, chronic raised lesion, bilaterally on the same anatomical area is uncommon. We reported a case of giant verruca vulgaris in a 25 year-old man on both legs that slowly enlarged and hardened in 5 years. It was a hyperkeratotic verruca vulgaris, grey brownish in color, circumscribe, round, and 4.0x3.0x1.0 cm in size on the right leg and 3.5x3.4x0.5 cm on the left leg and around 0.4cm raised from the skin surface. Histopathologic examination revealed compact hyperkeratosis/orthokeratosis, many koilocytes in the granular and upper spinous layer, acanthosis, and elongated rete ridges that were pointing radially toward the center of the lesion. The patient was successfully treated with surgical excision followed by split skin grafting.